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Biópsia do nervo sural na distrofia muscular miotônica Sural nerve biopsy in myotonic dystrophy
- Source :
- Arquivos de Neuro-Psiquiatria, Vol 54, Iss 1, Pp 19-24 (1996)
- Publication Year :
- 1996
- Publisher :
- Academia Brasileira de Neurologia (ABNEURO), 1996.
-
Abstract
- Foram estudados 12 pacientes com distrofia muscular miotônica com o objetivo de verificar o comprometimento do sistema nervoso periférico. Todos apresentavam os sinais e sintomas principais da doença. Nenhum tinha outras causas que pudessem justificar uma polineuropatia. Todos foram submetidos a biópsia do nervo sural com contagem de fibras mielínicas e realização de histograma. Dois não apresentavam histograma bimodal. Os pacientes mostraram redução do número de fibras mielínicas. Concluímos que a polineuropatia pode fazer parte do quadro clínico polimorfo da distrofia muscular miotônica.Twelve patients with myotonic dystrophy were studied to look for the involvement of the peripheral nervous system in this disease. All of them showed the main signs and symptoms of the disease. They did not have another causes to justify a polineuropathy. They were submitted to sural nerve biopsy with counting of myelinated fibers and histogram. Patients showed a reduction in the number of myelinated fibers and in two patients the histogram was unimodal. We concluded that polineuropathy may be another multisystemic manifestation of myotonic dystrophy.
Details
- Language :
- English
- ISSN :
- 0004282X and 16784227
- Volume :
- 54
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Arquivos de Neuro-Psiquiatria
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4a21e3738d4853b30a2151c1c6217b
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/S0004-282X1996000100003