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Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits

Authors :
Najate Benamer
Marie Vidal
Maddalena Balia
María Cecilia Angulo
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear. Here, the authors show that INs myelination shapes feedforward inhibition of mouse cortical sensory circuits and impacts whisker-mediated behaviour.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.48f6ab19e8ec4ac29d125dc718d5e455
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-18984-7