Association between obesity and chronic rhinosinusitis with nasal polyps: a national population-based study

Objectives We performed a cross-sectional analysis of data from the nationwide Korea National Health and Nutrition Examination Survey to evaluate the association between obesity and chronic rhinosinusitis with nasal polyps (CRSwNP) or without nasal polyp (CRSsNP).Design Retrospective cross-sectional analysis of health survey data.Setting Voluntary survey of representative South Korean populations.Participants In total, 32 384 individuals aged 19 years or older with available data on CRS and obesity were included.Primary and secondary outcome measures Diagnosis of CRSwNP or CRSsNP was performed by trained otolaryngologists through sinus endoscopy and surveys of medical history. General and central obesity was diagnosed using body mass index (BMI) and waist circumference (WC), respectively.Methods A multivariate logistic regression analysis was used to clarify the association between CRSwNP or CRSsNP and obesity according to BMI and WC. Non-obese individuals were recruited as controls.Results The prevalence of CRSwNP was higher in the general (OR, 1.438; 95% CI, 1.170 to 1.768; p