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Evaluating the anti-cancer potential and pharmacological in-sights of Physalis angulata Root Extract as a strong candidate for future research

Authors :
Jayachithra Ramakrishna Pillai
Adil Farooq Wali
Pooja Shivappa
Sirajunisa Talath
Sabry M. Attia
Ahmed Nadeem
Muneeb U. Rehman
Source :
Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 4, Pp 100410- (2024)
Publication Year :
2024
Publisher :
Elsevier, 2024.

Abstract

The research targeting the prevention of complications through natural constituents, instigated by the cancer has recently drawn much more attention over the globe. The research in this direction also revealed that the use of natural constituents would considered a promising strategy for diminishing the aforementioned disease and its consequences. Because of the easy availability and safe nature, the recent years, natural resources as strong anticancer agents. In this regard, here we introduced the possibility of using the methanolic extract of Physalis angulata root as a strong candidate and implemented the applicability of LC-MS to unveil the presence of various phytocompounds. The anticancer potential exhibited by Physalis angulata root followed by its ability to induce toxicity against the microbial population enhanced the interest in unveiling the phytochemical compounds including Absintholide, Curcumin dimer 1, Mytilin A, Ginsenoside F1, Encecalin , Ganoderic acid TQ, Alnustone, Rhamnetin 3-sophoroside, Gibberellin A14 aldehyde, Thiolutin, Euglobal III and Epomusenin B. The presence of various macro and micronutrients suggested that Physalis angulata is a prominent resource for future research targeting pharmacological research, especially anticancer research.

Details

Language :
English
ISSN :
1687157X
Volume :
22
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Journal of Genetic Engineering and Biotechnology
Publication Type :
Academic Journal
Accession number :
edsdoj.48e7579670424f0c8cc8676fb99a89b1
Document Type :
article
Full Text :
https://doi.org/10.1016/j.jgeb.2024.100410