Back to Search Start Over

The immune factors driving DNA methylation variation in human blood

Authors :
Jacob Bergstedt
Sadoune Ait Kaci Azzou
Kristin Tsuo
Anthony Jaquaniello
Alejandra Urrutia
Maxime Rotival
David T. S. Lin
Julia L. MacIsaac
Michael S. Kobor
Matthew L. Albert
Darragh Duffy
Etienne Patin
Lluís Quintana-Murci
Milieu Intérieur Consortium
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Many studies assess epigenetic marks in white blood cells, but it is unclear how much immune factors affect the epigenome. Here, the authors show that fine-scale blood cell composition and cytomegalovirus infection affect the DNA methylome of adults.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.485673d79fb4ce58ac6fd1885bfaa9c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33511-6