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Sequential role of RAD51 paralog complexes in replication fork remodeling and restart
- Source :
- Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
- Publication Year :
- 2020
- Publisher :
- Nature Portfolio, 2020.
-
Abstract
- Replication stress has been associated with transient remodelling of replication intermediates into reversed forks, followed by efficient fork restart. Here the authors systematically analyse the role of RAD51 paralogs in these transactions, providing insights on the mechanistic role of different complexes of these proteins.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 33346089
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.46eeddebb333460895c7cc3055c262ef
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-020-17324-z