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Changes in the prevalence of hepatitis B and metabolic abnormalities among young men in Korea
- Source :
- The Korean Journal of Internal Medicine, Vol 37, Iss 5, Pp 1082-1087 (2022)
- Publication Year :
- 2022
- Publisher :
- The Korean Association of Internal Medicine, 2022.
-
Abstract
- Changes in the prevalence of disease over time provide valuable information from a public health perspective. We used data from Korea Military Manpower Administration medical examinations for conscription between 2003 and 2019 (n = 5,355,941), which involved young men aged 19 years, to observe changes in liver disease over time at a population level. Trends in the prevalence of hepatitis B surface antigen (HBsAg), elevated alanine aminotransferase (ALT) levels, the fibrosis-4 (FIB-4) index, obesity, and hypertension were assessed. The prevalence of HBsAg steadily decreased from 3.19% for men born in 1984 to 0.18% for men born in 2000. Among HBsAg-negative subjects, the prevalence of elevated ALT levels increased from 13.15% for men born in 1986 to 16.48% for men born in 2000. The prevalence of obesity, hypertension and the proportion with high FIB-4 scores (≥ 1.45) also increased. This population-based nationwide analysis showed a decreasing trend of HBsAg and increasing trends of possible non-alcoholic fatty liver disease.
- Subjects :
- hepatitis b
chronic
alanine transaminase
korea
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 12263303 and 20056648
- Volume :
- 37
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- The Korean Journal of Internal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.46acc362f72d428abe96e74412215afc
- Document Type :
- article
- Full Text :
- https://doi.org/10.3904/kjim.2021.452