Clinical features and risk factors for development of post-infectious bronchiolitis obliterans in children

Abstract Background Post-infectious bronchiolitis obliterans (PIBO) is a severe form of chronic obstructive lung disease secondary to severe respiratory tract infections. Knowledge of pediatric PIBO development-associated risk factors may improve selection of appropriate early therapeutic interventions. Objective The aim of this study was to describe the clinical characteristics of children diagnosed with PIBO, and identify the risk factors for development of PIBO after adenovirus pneumonia. Methods First, a retrospective observational study was performed of 308 pediatric patients with PIBO (ages