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DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy

Authors :
Suchetan Pal
Angana Ray
Chrysafis Andreou
Yadong Zhou
Tatini Rakshit
Marek Wlodarczyk
Masatomo Maeda
Ricardo Toledo-Crow
Naxhije Berisha
Jiang Yang
Hsiao-Ting Hsu
Anton Oseledchyk
Jagannath Mondal
Shengli Zou
Moritz F. Kircher
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Currently available Raman scanners are limited in speed to acquire images of clinically relevant sizes in cancer imaging. Here, the authors developed a DNA based design principle for Raman-Fluorescence bimodal nanoparticles and demonstrate real-time, high precision image-guided tumor resections and photothermal ablation of cancer.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.45b115ea90ac4c3fb323dba659f6adf6
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-09173-2