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Perspectives on skeletal muscle stem cells

Authors :
F. Relaix
M. Bencze
M. J. Borok
A. Der Vartanian
F. Gattazzo
D. Mademtzoglou
S. Perez-Diaz
A. Prola
P. C. Reyes-Fernandez
A. Rotini
Taglietti
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Skeletal muscle has a remarkable regenerative capacity, which can largely be attributed to resident muscle stem cells (MuSCs). Here, the authors review the molecular mechanisms regulating MuSC quiescence, activation and proliferation, how these processes are regulated by the stem cell niche, and the role of MuSCs in neuromuscular diseases.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.458d5c3a713043e5bfa5170ab7c291af
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-20760-6