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Polymeric nanoparticles—Promising carriers for cancer therapy

Authors :
Xiao Xiao
Fei Teng
Changkuo Shi
Junyu Chen
Shuqing Wu
Bao Wang
Xiang Meng
Aniekan Essiet Imeh
Wenliang Li
Source :
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Publication Year :
2022
Publisher :
Frontiers Media S.A., 2022.

Abstract

Polymeric nanoparticles (NPs) play an important role in controlled cancer drug delivery. Anticancer drugs can be conjugated or encapsulated by polymeric nanocarriers, which are known as polymeric nanomedicine. Polymeric nanomedicine has shown its potential in providing sustained release of drugs with reduced cytotoxicity and modified tumor retention, but until now, few delivery systems loading drugs have been able to meet clinical demands, so more efforts are needed. This research reviews the current state of the cancer drug-loading system by exhibiting a series of published articles that highlight the novelty and functions from a variety of different architectures including micelles, liposomes, dendrimers, polymersomes, hydrogels, and metal–organic frameworks. These may contribute to the development of useful polymeric NPs to achieve different therapeutic purposes.

Details

Language :
English
ISSN :
22964185
Volume :
10
Database :
Directory of Open Access Journals
Journal :
Frontiers in Bioengineering and Biotechnology
Publication Type :
Academic Journal
Accession number :
edsdoj.45166268316f4b0bae50e0708df0997a
Document Type :
article
Full Text :
https://doi.org/10.3389/fbioe.2022.1024143