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Indications and Limits of Surgery for Spinal Metastases Derived from Lung Cancer: A Single-Center Experience

Authors :
Silvia Terzi
Federica Trentin
Cristiana Griffoni
Elisa Carretta
Stefano Bandiera
Cristina Ferrari
Fabio Vita
Alberto Righi
Margherita Maioli
Dario De Biase
Annalisa Monetta
Giovanni Barbanti Brodano
Gisberto Evangelisti
Marco Girolami
Valerio Pipola
Marco Gambarotti
Alessandro Gasbarrini
Source :
Diagnostics, Vol 13, Iss 12, p 2093 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Lung cancer is the second most frequently diagnosed cancer in the world, and surgery is an integral part of the treatment for spinal metastases. The aims of this retrospective study were to assess the overall survival of surgically treated patients affected by lung cancer spinal metastases and identify any factors related to a better survival rate. We recruited 56 consecutive patients (34 male and 22 female) surgically treated for metastatic lung cancer in the spine from 2009 to 2019. Surgical indications were based on a previously published and validated flow chart following a multidisciplinary evaluation. We assessed the localization of vertebral metastases, the presence of other bone or visceral metastases, neurological status according to the Frankel score, ambulatory autonomy, and general status, measured with the Karnofsky performance scale. The expected prognosis was retrospectively assessed according to the revised Tokuhashi score. The median survival was 8.1 months, with over a third of patients surviving more than 1 year. We observed a global improvement in all clinical parameters after surgical treatment. The Tokuhashi predictive score did not correlate with survival after surgery. The results of this study suggest that the surgical treatment of symptomatic spinal metastases from lung cancer can improve quality of life, even in patients with a shorter life expectancy, by controlling pain and improving autonomy.

Details

Language :
English
ISSN :
20754418
Volume :
13
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Diagnostics
Publication Type :
Academic Journal
Accession number :
edsdoj.44e932b5268742ada0b90aaaf9dde806
Document Type :
article
Full Text :
https://doi.org/10.3390/diagnostics13122093