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Effects of hydrogen-rich water on hamsters with experimental myeloid tumor

Authors :
Reneta Toshkova
Nikolai Neshev
Ignat Ignatov
Fabio Huether
Alexander I. Ignatov
Ivan Angushev
Source :
Libri Oncologici, Vol 51, Iss 2-3, Pp 85-96 (2023)
Publication Year :
2023
Publisher :
University Hospital for Tumors, 2023.

Abstract

This paper presents the results of an in vivo study of the antitumor effect of hydrogen-rich water in hamsters with experimental myeloid tumors. Hydrogen-rich EVOdrop water (HEW) with a molecular hydrogen (H2) concentration of 1.2 ppm. pH=7.3, and oxidation-reduction potential (ORP) of (-390 mV) as basic parameters were obtained with the EVObooster apparatus. The myeloid tumor was implanted subcutaneously on the back of Golden Syrian hamsters used for the experiment. The effect of HEW on biometric parameters of tumor growth, namely 18 hematological parameters and some hematological biomarkers (indices) was evaluated. The blood sera from experimental and control animals were analyzed using the Non-equilibrium energy spectrum (NES) and the Differential non-equilibrium energy spectrum (DNES) spectral methods. The results showed a protective antitumor effect of HEW seen by a decrease in tumor uptake rate, a decrease in mortality, an increase in survival time, a normalizing effect on hematological parameters and biomarkers (N/LR, WBC/LR, PLT/LR), and an increase in energy between water molecules in blood serum in hamsters with experimental myeloid tumor. The results show that HEW has anticancer potential that could be used with conventional chemotherapeutics to develop new treatment strategies as well as cancer prevention.

Details

Language :
English
ISSN :
03008142 and 25843826
Volume :
51
Issue :
2-3
Database :
Directory of Open Access Journals
Journal :
Libri Oncologici
Publication Type :
Academic Journal
Accession number :
edsdoj.44c99c9baf6460c9d78aaf37868a60c
Document Type :
article
Full Text :
https://doi.org/10.20471/LO.2023.51.02-03.13