Study of 320-slice dynamic volume CT perfusion in different pathologic types of kidney tumor: preliminary results.

OBJECTIVE: To investigate microcirculatory differences between pathologic types of kidney tumor using 320-slice dynamic volume CT perfusion. METHODS: Perfusion imaging with 320-slice dynamic volume CT was prospectively performed in 85 patients with pathologically proven clear cell renal cell carcinoma (RCC) (n = 66), papillary RCC (n = 7), chromophobe RCC (n = 5), angiomyolipoma (AML) with minimal fat (n = 7), or RCC (n = 78). Equivalent blood volume (Equiv BV), permeability surface-area product (PS; clearance/unit volume = permeability), and blood flow (BF) of tumor and normal renal cortex were measured and analyzed. Effective radiation dose was calculated. RESULTS: There was a significant difference in all three parameters between tumor and normal renal cortex (P