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Differential geometry, a possible avenue for thermal ablation in oncology?
- Source :
- Condensed Matter Physics, Vol 27, Iss 3 (2024)
- Publication Year :
- 2024
- Publisher :
- Institute for Condensed Matter Physics, 2024.
-
Abstract
- We report a model for hyperthermia therapies based on heat diffusion in a biological tissue containing a topological defect. Biological tissues behave like active liquid crystals with the presence of topological defects which are likely to anchor tumors during the metastatic phase of cancer evolution and the therapy challenge is to destroy the cancer cells without damaging surrounding healthy tissues. The defect creates an effective non-Euclidean geometry for low-energy excitations, modifying the bio-heat equation. Applications to protocols of thermal ablation for various biological tissues (liver, prostate, and skin) is analyzed and discussed.
- Subjects :
- differential geometry
bioheat transport
thermal ablation
Physics
QC1-999
Subjects
Details
- Language :
- English
- ISSN :
- 1607324X and 22249079
- Volume :
- 27
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Condensed Matter Physics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.447a47dda451fa53543ea1769c24c
- Document Type :
- article
- Full Text :
- https://doi.org/10.5488/cmp.27.33201