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Ultracompact 3D microfluidics for time-resolved structural biology

Authors :
Juraj Knoška
Luigi Adriano
Salah Awel
Kenneth R. Beyerlein
Oleksandr Yefanov
Dominik Oberthuer
Gisel E. Peña Murillo
Nils Roth
Iosifina Sarrou
Pablo Villanueva-Perez
Max O. Wiedorn
Fabian Wilde
Saša Bajt
Henry N. Chapman
Michael Heymann
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

There is a need for more robust sample delivery methods for serial crystallography. Here the authors present the design and characterization of ultracompact 3D microfluidic devices that can be printed, which require less sample, have a lower background signal and allow 3D mixing for time resolved experiments.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.443090b0fc014b6fbd18956de00bb956
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-14434-6