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Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo

Authors :
Jimena Perez-Vargas
Fouzia Amirache
Bertrand Boson
Chloé Mialon
Natalia Freitas
Camille Sureau
Floriane Fusil
François-Loïc Cosset
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Hepatitis D virus (HDV) relies on a helper virus to package and transmit its ribonucleoprotein (RNP). Here, Perez-Vargas et al. show that HDV can use envelope proteins from HBV-unrelated viruses, including HCV and flaviviruses, to propagate in vitro and in humanized mice.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.442be38e30c54650a97b9c860a6723d3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-10117-z