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The non-coding RNA landscape of human hematopoiesis and leukemia

Authors :
Adrian Schwarzer
Stephan Emmrich
Franziska Schmidt
Dominik Beck
Michelle Ng
Christina Reimer
Felix Ferdinand Adams
Sarah Grasedieck
Damian Witte
Sebastian Käbler
Jason W. H. Wong
Anushi Shah
Yizhou Huang
Razan Jammal
Aliaksandra Maroz
Mojca Jongen-Lavrencic
Axel Schambach
Florian Kuchenbauer
John E. Pimanda
Dirk Reinhardt
Dirk Heckl
Jan-Henning Klusmann
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

While micro-RNAs are known regulators of haematopoiesis and leukemogenesis, the role of long non-coding RNAs is less clear. Here the authors provide a non-coding RNA expression landscape of the human hematopoietic system, highlighting their role in the formation and maintenance of the human blood hierarchy.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.43fcdb64f949d09ac6436b134eb
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-00212-4