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Phage Display Technology in Biomarker Identification with Emphasis on Non-Cancerous Diseases

Authors :
Mohammad Sadraeian
Reza Maleki
Mahta Moraghebi
Abasalt Bahrami
Source :
Molecules, Vol 29, Iss 13, p 3002 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

In recent years, phage display technology has become vital in clinical research. It helps create antibodies that can specifically bind to complex antigens, which is crucial for identifying biomarkers and improving diagnostics and treatments. However, existing reviews often overlook its importance in areas outside cancer research. This review aims to fill that gap by explaining the basics of phage display and its applications in detecting and treating various non-cancerous diseases. We focus especially on its role in degenerative diseases, inflammatory and autoimmune diseases, and chronic non-communicable diseases, showing how it is changing the way we diagnose and treat illnesses. By highlighting important discoveries and future possibilities, we hope to emphasize the significance of phage display in modern healthcare.

Details

Language :
English
ISSN :
14203049
Volume :
29
Issue :
13
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.43e94da169342548ebd1a21ac6ec078
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules29133002