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Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage
- Source :
- Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
- Publication Year :
- 2017
- Publisher :
- Nature Portfolio, 2017.
-
Abstract
- Lipid droplets (LDs) are cellular organelles dedicated to triacylglycerol storage that can undergo fusion and dissociation events. Here the authors show that formin-like 1-dependent acto-myosin assembly on LDs facilitates their dissociation and, as a consequence, affects hydrolysis and storage of triacylglycerols.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 8
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.431a9166504d47adae4b3f6abb8d16
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms14858