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Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis
- Source :
- Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
- Publication Year :
- 2020
- Publisher :
- Fundação Oswaldo Cruz (FIOCRUZ), 2020.
-
Abstract
- Angiostrongylus costaricensis is the causative agent of abdominal angiostrongyliasis, a zoonotic infection that may produce severe eosinophilic enterocolitis or hepatitis in humans. Parasites are usually not released in stools and serology has an important role in diagnosis. Since cross-reactivity is demonstrated between A. costaricensis and another metastrongylid worm, A. cantonensis, we tested heterologous recombinant galectin as a probe in an immunochromatographic rapid diagnostic test (ICT-RDT) for detection of anti-A. costaricensis antibodies. Almost all (11/12) positive control sera from A. costaricensis infected patients were positive at ICT RDT. These are preliminary indications that r-galectin ICT-RDT is useful for diagnosing A. costaricensis infection.
Details
- Language :
- English
- ISSN :
- 16788060 and 00740276
- Volume :
- 115
- Database :
- Directory of Open Access Journals
- Journal :
- Memorias do Instituto Oswaldo Cruz
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.427d5fa5024211a1939cb53bf85f96
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/0074-02760200201