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Potential Protective Function of Adiponectin in Diabetic Retinopathy

Authors :
Hui Deng
Meichen Ai
Yuchen Cao
Liyang Cai
Xi Guo
Xiongyi Yang
Guoguo Yi
Min Fu
Source :
Ophthalmology and Therapy, Vol 12, Iss 3, Pp 1519-1534 (2023)
Publication Year :
2023
Publisher :
Adis, Springer Healthcare, 2023.

Abstract

Abstract Adiponectin, one of the most ubiquitous adipokines found in the blood, plays a major role in glucolipid metabolism and energy metabolism and regulation. In recent years, a growing body of research indicates that adiponectin also plays a significant role in diabetic retinopathy. In the present review, we specifically address the protective effects of adiponectin on the development and progression of diabetic retinopathy through improvement in insulin resistance, alleviation of oxidative stress, limiting of inflammation, and prevention of vascular remodeling, with the aim to explore new potential approaches and targets for the prevention and treatment of diabetic retinopathy.

Details

Language :
English
ISSN :
21938245 and 21936528
Volume :
12
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Ophthalmology and Therapy
Publication Type :
Academic Journal
Accession number :
edsdoj.427ce292041b46449c41f1cea15d5134
Document Type :
article
Full Text :
https://doi.org/10.1007/s40123-023-00702-3