Vitrectomy in Diabetic Macular Edema

Purpose: The foveal avascular zone (FAZ) has been reported to decrease after anti-VEGF injections in diabetic macular edema (DME) in the long term. This study aimed to present the changes in swept-source OCT angiography after vitrectomy in patients with DME. Design: Retrospective interventional study. Participants: Thirty-five eyes were included (mean age: 62 years). Methods: Patients were followed for 12 months after vitrectomy with internal limiting membrane peeling for DME. Main Outcome Measures: The following parameters were measured: central retinal thickness (CRT), central choroidal thickness, superficial FAZ, deep FAZ (dFAZ), and vessel density in the superficial and deep retinal layers (dVD). Results: The CRT and superficial FAZ significantly decreased after surgery (401 μm–338 μm; P