Effect of early enteral nutrition combined with parenteral nutrition on patients after pancreaticoduodenectomy

Objective To investigate the effect of early enteral nutrition combined with parenteral nutrition on patients received pancreaticoduodenectomy. Methods A retrospective analysis of 222 patients who underwent pancreaticoduodenectomy at Nanjing Drum Tower Hospital from January 2012 to November 2018 was conducted. According to different feeding methods, patients were divided into two groups: early enteral nutrition combined with parenteral nutrition group (EEN+PN group, n=141) and total parenteral nutrition group (TPN group, n=81). The nutritional indicator, liver function at 1 day before operation and 6 days after operation, postoperative complications and hospital stay were compared between the two groups. Results Compared with TPN group, the decrease difference of prealbumin (PAB) in EEN+PN group was statistically significant (P