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Building a Chinese pan-genome of 486 individuals

Authors :
Qiuhui Li
Shilin Tian
Bin Yan
Chi Man Liu
Tak-Wah Lam
Ruiqiang Li
Ruibang Luo
Source :
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Qiuhui Li et al. report a pan-genome sequence study in Han Chinese genomes. They find 276 Mbp of DNA sequences (absent in the current human reference), and report that 46.646 Mbp common sequences improved the accuracy of variant calling and mapping rate when added to the reference genome.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.40dbb44391654e2c801fd88dfa21b5bd
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-021-02556-6