ASSOCIATION OF NEUTROPHIL-TO-LYMPHOCYTE RATIO, PLATELET-TO-LYMPHOCYTE RATIO, AND SYSTEMIC IMMUNE-INFLAMMATION INDEX WITH THE DEGREE OF ADENOID HYPERTROPHY IN CHILDREN

Objective To investigate the association of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) with the degree of adenoid hypertrophy in children. Methods This study was conducted for 181 children who attended Department of Otorhinolaryngology & Head and Neck Surgery in our hospital and were diagnosed with adenoid hypertrophy by fibrolaryngoscopy from February 2020 to February 2021. According to the type and degree of adenoid hypertrophy, the children were divided into pathological adenoid hypertrophy (degree Ⅲ-Ⅳ hypertrophy) group and physiological adenoid hypertrophy (degree Ⅰ-Ⅱhypertrophy) group (group A), and the pathological adenoid hypertrophy group was further divided into degree Ⅲ hypertrophy group (group B) and degree Ⅳ hypertrophy group (group C). Plasma NLR, PLR, and SII were compared between the above groups, and the influence of these indices on the degree of adenoid hypertrophy in children were analyzed. Results There were significant differences in plasma NLR and SII between the three groups (F=27.346, 22.533,P0.05); group C had significantly higher plasma NLR and SII than groups A and B (P