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A multicenter retrospective study on the real-world outcomes of autologous vs. allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphoma in China
- Source :
- Chinese Medical Journal, Vol 134, Iss 13, Pp 1584-1592 (2021)
- Publication Year :
- 2021
- Publisher :
- Wolters Kluwer, 2021.
-
Abstract
- Abstract. Background:. There were few studies on real-world data about autologous hematopoietic stem cell transplantation (auto-HSCT) or allogeneic HSCT (allo-HSCT) in peripheral T-cell lymphoma (PTCL). This study aimed to investigate the clinical outcomes of patients who received auto-HSCT or allo-HSCT in China. Methods:. From July 2007 to June 2017, a total of 128 patients who received auto-HSCT (n = 72) or allo-HSCT (n = 56) at eight medical centers across China were included in this study. We retrospectively collected their demographic and clinical data and compared the clinical outcomes between groups. Results:. Patients receiving allo-HSCT were more likely to be diagnosed with stage III or IV disease (95% vs. 82%, P = 0.027), bone marrow involvement (42% vs. 15%, P = 0.001), chemotherapy-resistant disease (41% vs. 8%, P = 0.001), and progression disease (32% vs. 4%, P
- Subjects :
- Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 03666999, 25425641, and 00000000
- Volume :
- 134
- Issue :
- 13
- Database :
- Directory of Open Access Journals
- Journal :
- Chinese Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3feb198c594d4ca7b1d968b927c70681
- Document Type :
- article
- Full Text :
- https://doi.org/10.1097/CM9.0000000000001575