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Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need

Authors :
Neil Cherian
Alison Bettis
Arminder Deol
Arun Kumar
Jose Luis Di Fabio
Amol Chaudhari
Solomon Yimer
Raafat Fahim
Timothy Endy
Source :
npj Vaccines, Vol 8, Iss 1, Pp 1-8 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Abstract Chikungunya is an arboviral disease caused by the chikungunya virus (CHIKV) afflicting tropical and sub-tropical countries worldwide. It has been identified as a priority pathogen by the Coalition for Epidemics Preparedness Innovations (CEPI) and as an emerging infectious disease (EID) necessitating further action as soon as possible by the World Health Organization (WHO). Recent studies suggest that disability-adjusted life years (DALYs) due to CHIKV infection are as high as 106,089 DALYs lost globally. Significant progress has been made in the development of several vaccines, aimed at preventing CHIKV infections. This perspective article summarizes CEPI’s efforts and strategic considerations for developing a CHIKV vaccine and ensuring equitable access for CHIKV endemic countries.

Details

Language :
English
ISSN :
20590105
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
npj Vaccines
Publication Type :
Academic Journal
Accession number :
edsdoj.3f82c20087b043feb1c1f6fdb7d0cfa1
Document Type :
article
Full Text :
https://doi.org/10.1038/s41541-023-00722-x