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A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Therapies and vaccines for COVID-19, caused by the SARS-CoV-2 viral pandemic, are urgently needed. Here the authors establish and screen an antibody library from a convalescent COVID-19 patient to isolate a neutralizing antibody with the ability to reduce viral titer and alleviate symptoms in ferret, hamster, and rhesus monkey infection models.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3f24e9305e4570b111ea9285c26144
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-020-20602-5