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Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression

Authors :
Annunziata Di Domenico
Christodoulos P. Pipinikas
Renaud S. Maire
Konstantin Bräutigam
Cedric Simillion
Matthias S. Dettmer
Erik Vassella
Chrissie Thirlwell
Aurel Perren
Ilaria Marinoni
Source :
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
3
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.3f12048273d452cbac17af8d0e13581
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-020-01479-y