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Pixelated spatial gene expression analysis from tissue

Authors :
A. Ganguli
A. Ornob
N. Spegazzini
Y. Liu
G. Damhorst
T. Ghonge
B. Thornton
C. J. Konopka
W. Dobrucki
S. E. Clare
R. Bhargava
A. M. Smith
F. Kosari
R. Bashir
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Spatial localization of genetic information is important for tissue heterogeneity but difficult to capture with current analytical techniques. Here the authors present “Pixelated RT-LAMP”, an approach that uses parallel on-chip reactions to provide the distribution of target sequences directly from tissue.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3f0ffa80cb5a4920885a266e00c14507
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-02623-9