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A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

Authors :
Ningfei Li
Juan Carlos Baldermann
Astrid Kibleur
Svenja Treu
Harith Akram
Gavin J. B. Elias
Alexandre Boutet
Andres M. Lozano
Bassam Al-Fatly
Bryan Strange
Juan A. Barcia
Ludvic Zrinzo
Eileen Joyce
Stephan Chabardes
Veerle Visser-Vandewalle
Mircea Polosan
Jens Kuhn
Andrea A. Kühn
Andreas Horn
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Li et al. analyzed structural connectivity of deep brain stimulation electrodes in 50 patients suffering from obsessive-compulsive disorder operated at four centers. Connectivity to a specific tract within the anterior limb of the internal capsule was associated with optimal treatment response across cohorts, surgeons and centers.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3f03043ad0d44175a12a3f056b070b93
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-16734-3