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Characterizing rare and low-frequency height-associated variants in the Japanese population

Authors :
Masato Akiyama
Kazuyoshi Ishigaki
Saori Sakaue
Yukihide Momozawa
Momoko Horikoshi
Makoto Hirata
Koichi Matsuda
Shiro Ikegawa
Atsushi Takahashi
Masahiro Kanai
Sadao Suzuki
Daisuke Matsui
Mariko Naito
Taiki Yamaji
Motoki Iwasaki
Norie Sawada
Kozo Tanno
Makoto Sasaki
Atsushi Hozawa
Naoko Minegishi
Kenji Wakai
Shoichiro Tsugane
Atsushi Shimizu
Masayuki Yamamoto
Yukinori Okada
Yoshinori Murakami
Michiaki Kubo
Yoichiro Kamatani
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Thousands of genetic loci are known to associate with human height, but these are mainly based on studies in European ancestry populations. Here, Akiyama et al. construct a genotype reference panel for the Japanese population followed by GWAS and report 573 height associated variants in 191,787 Japanese.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3eeeb8172daf496ab4e694b177dd837b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-12276-5