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Efficacy of Single Tocilizumab Administration in an 88-Year-Old Patient with Severe COVID-19 and a Mini Literature Review

Authors :
Cid Ould Ouali
Nadia Ladjouzi
Khidher Tamas
Hendriniaina Raveloson
Jihene Ben Hassen
Nesrine El Omeiri
Georges Zouloumis
Mohamed Moataz Al Zoabi
Muneer Asadi
Aziza Jhouri
Joël Schlatter
Source :
Geriatrics, Vol 7, Iss 1, p 22 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

The new coronavirus disease 2019 (COVID-19) could be associated with elevated inflammatory cytokine levels, suggesting the involvement of cytokine release syndrome. This syndrome is characterized by release of interleukin 6 correlated with COVID-19 severity and mortality. Targeting IL-6 with Tocilizumab treatment could be a potential therapeutic option for old patients. We report the case of an 88-year-old man with COVID-19 disease who presented at the admission with anemia, fever, oxygen desaturation (92%), and inflammatory syndrome (C-reactive protein (CRP) at 182.5 mg/L; reference range

Details

Language :
English
ISSN :
23083417
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Geriatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.3e9dfac8ecc4ac1a9a53aea12885208
Document Type :
article
Full Text :
https://doi.org/10.3390/geriatrics7010022