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Association between dopamine receptor D2 IA gene polymorphism (rs1800497) and personality traits
- Source :
- SAGE Open Medicine, Vol 12 (2024)
- Publication Year :
- 2024
- Publisher :
- SAGE Publishing, 2024.
-
Abstract
- Objective: This study aimed to find a potential association between the DRD2 Taq 1A gene polymorphism (rs1800497 C32806T) and personality traits. Methods: In all, 249 youths were recruited for this study. The Short-form Revised Eysenck Personality Questionnaire was administered to assess personality traits. The participants were genotyped for the DRD2 Taq 1A polymorphism using the polymerase chain reaction-restriction fragment length polymorphism method. Statistical analysis was carried out to find a possible association between the genotypes and aspects of personality traits assessed. Results: The frequencies of the A1 and A2 alleles in our sampled population were 215 (43.2%) and 283 (56.8%), while the frequencies of A1A1, A1A2, and A2A2 were 67 (26.9%), 81 (32.5%), and 101 (40.6%), respectively. The study population was not in Hardy-Weinberg equilibrium ( χ 2 = 17.64, p
- Subjects :
- Medicine (General)
R5-920
Subjects
Details
- Language :
- English
- ISSN :
- 20503121
- Volume :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- SAGE Open Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3e92b5c6222b4af5aca324f6b5e1b5dd
- Document Type :
- article
- Full Text :
- https://doi.org/10.1177/20503121241241922