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Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer
- Source :
- World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-15 (2022)
- Publication Year :
- 2022
- Publisher :
- BMC, 2022.
-
Abstract
- Highlights A total of 309 CD8 T cell-related genes and 120 activated memory CD4 T cell-related genes were screened in liver cancer tumor samples. Forty-four chemical small-molecule–target interaction pairs associated with activated memory CD4 T cells and 276 pairs associated with CD8 T cells were screened. Upregulated expression of T cell-related genes including EOMES, CST7, and CD5L indicated the favorable prognosis of liver cancer.
Details
- Language :
- English
- ISSN :
- 14777819
- Volume :
- 20
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- World Journal of Surgical Oncology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3e600cc33b064ebfb2d199370f723488
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s12957-021-02461-6