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NLR, MLR, and PLR are adverse prognostic variables for sleeve lobectomy within non‐small cell lung cancer

Authors :
Rui Han
Fan Zhang
Qian Hong
Djaferi Visar
Chang Zhan
Chenguang Zhao
Fuquan Wang
Sining Zhang
Fang Li
Jiagen Li
Juwei Mu
Source :
Thoracic Cancer, Vol 15, Iss 24, Pp 1792-1804 (2024)
Publication Year :
2024
Publisher :
Wiley, 2024.

Abstract

Abstract Background The goal of the research was to examine the value of peripheral blood indicators in forecasting survival and recurrence among people suffering central‐type non‐small cell lung cancer (NSCLC) undergoing sleeve lobectomy (SL). Methods Clinical information was gathered from 146 individuals suffering from NSCLC who had SL at our facility between January 2014 and May 2023. Peripheral blood neutrophil lymphocyte ratio (NLR), monocyte lymphocyte ratio (MLR), and platelet lymphocyte ratio (PLR) levels were determined by receiver operating characteristic (ROC) curve to establish the threshold points. Kaplan–Meier survival analysis was employed to evaluate the prognostic value of different groupings, and both univariate and multivariate Cox proportional hazards model (referred to as COX) were performed. Results The disease‐free survival (DFS) and overall survival (OS) cutoff values were carried out via ROC analysis. Kaplan–Meier survival analysis revealed notable differences in OS for NLR (≥2.196 vs.

Details

Language :
English
ISSN :
17597714 and 17597706
Volume :
15
Issue :
24
Database :
Directory of Open Access Journals
Journal :
Thoracic Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.3d0e74a772b740f4994a0899a9cb7089
Document Type :
article
Full Text :
https://doi.org/10.1111/1759-7714.15405