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P4.30 ENDOTHELIAL DYSFUNCTION AND CARDIOVASCULAR RISK PROFILE IN PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION
- Source :
- Artery Research, Vol 7, Iss 10 (2013)
- Publication Year :
- 2013
- Publisher :
- BMC, 2013.
-
Abstract
- Background/aims: The impact of chronic hepatitis C (HCV) virus infection on atherosclerosis is controversial. In this pilot clinical study, we examined whether HCV patients significantly differed in markers of subclinical atherosclerosis compared to patients with alcohol-related chronic liver disease. Methods: We enrolled 21 consecutive adult patients with HCV and 11 patients with alcohol-related chronic liver disease after detoxification from alcohol. Common carotid intima-media thickness (CIMT) and brachial artery flow mediated vasodilation (FMD) by ultrasonography and carotid-femoral pulse wave velocity (cf-PWV) by applanation tonometry were measured in all participants by a single trained operator, who was blind to clinical features of participants. Results: Compared with those with alcohol-related liver disease, patients with HCV had markedly lower FMD (4.57±1.50 vs. 9.84±3.60%, p
Details
- Language :
- English
- ISSN :
- 18764401
- Volume :
- 7
- Issue :
- 10
- Database :
- Directory of Open Access Journals
- Journal :
- Artery Research
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3d05bb651d495382affd7d54ebe60d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.artres.2013.10.148