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Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection

Authors :
Lu Dongming
Yaqoob Obaid
Kumar Manish
Kushwah Ajay Singh
Sharma Rahul Kumar
Kumar Devinder
Mavai Yogendra
Khan Rukaiya
Source :
Acta Pharmaceutica, Vol 73, Iss 1, Pp 29-42 (2023)
Publication Year :
2023
Publisher :
Sciendo, 2023.

Abstract

This century’s most serious catastrophe, COVID-19, has been dubbed “the most life-threatening disaster ever”. Asthmatic persons are even more prone to COVID-19’s complex interplay with the underlying inflammatory condition. In order to protect themselves against COVID-19, asthmatic patients must be very vigilant in their usage of therapeutic techniques and drugs (e.g., bronchodilators, 5-lipoxygenase inhibitors), which may be accessed to deal with mild, moderate, and severe COVID-19 indications. People with asthma may have more severe COVID-19 symptoms, which may lead to a worsening of their condition. Several cytokines were found to be elevated in the bronchial tracts of patients with acute instances of COVID-19, suggesting that this ailment may aggravate asthma episodes by increasing inflammation. The intensity of COVID-19 symptoms is lessened in patients with asthma who have superior levels of T-cells. Several antibiotics, antivirals, antipyretics, and anti-inflammatory drugs have been suggested to suppress COVID-19 symptoms in asthmatic persons. Furthermore, smokers are more likely to have aggravated repercussions in COVID-19 infection. Being hospitalized to critical care due to COVID-19, needing mechanical breathing, and suffering from serious health repercussions, are all possible outcomes for someone who has previously smoked. Smoking damages airways and alveoli, which significantly raises the risk of COVID-19-related health complications. Patients with a previous record of smoking are predisposed to severe COVID-19 disease symptoms that essentially require a combination of bronchodilators, mucolytics, antivirals, and antimuscarinic drugs, to cope with the situation. The present review discusses the care and management of asthmatic and smoker patients in COVID-19 infection.

Details

Language :
English
ISSN :
18469558
Volume :
73
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Acta Pharmaceutica
Publication Type :
Academic Journal
Accession number :
edsdoj.3c36ee230c054c37943a477a43349588
Document Type :
article
Full Text :
https://doi.org/10.2478/acph-2023-0002