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DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- FG-Nups are disordered proteins in the nuclear pore complex (NPC) where they selectively control nuclear transport. Here authors build NPC-mimics based on DNA origami rings which attach a certain numbers of Nups to analyse those nanopores by cryoEM and conductance measurements.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3c16edd0fd33457389226bffa28bd552
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-03313-w