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Wearable Inertial Devices in Duchenne Muscular Dystrophy: A Scoping Review

Authors :
Elisa Panero
Rossella D’Alessandro
Ilaria Cavallina
Chiara Davico
Tiziana Mongini
Laura Gastaldi
Federica Ricci
Source :
Applied Sciences, Vol 13, Iss 3, p 1268 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

In clinical practice and research, innovative digital technologies have been proposed for the characterization of neuromuscular and movement disorders through objective measures. Among these, wearable devices prove to be a suitable solution for tele-monitoring, tele-rehabilitation, and daily activities monitoring. Inertial Measurement Units (IMUs) are low-cost, compact, and easy-to-use wearable devices that evaluate kinematics during different movements. Kinematic variables could support the clinical evaluation of the progression of some neuromuscular diseases and could be used as outcome measures. The current review describes the use of IMUs for the biomechanical assessment of meaningful outcome measures in individuals affected by Duchenne muscular dystrophy (DMD). The PRISMA methodology was used and the search was conducted in different databases (Scopus, Web of Science, PubMed). A total of 23 articles were examined and classified according to year of publication, ambulatory/non-ambulatory subjects, and IMU positioning on human body. The analysis points out the recent regulatory identification of Stride Velocity 95th Centile as a new endpoint in therapeutic DMD trials when measured continuously from a wearable device, while only a few studies proposed the use of IMUs in non-ambulatory patients. Clinical recognition of reliable and accurate outcome measures for the upper body is still a challenge.

Details

Language :
English
ISSN :
20763417
Volume :
13
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Applied Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.3bcddd7540b94c26b583ef612839f9fc
Document Type :
article
Full Text :
https://doi.org/10.3390/app13031268