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Isovitexin modulates autophagy in Alzheimer’s disease via miR-107 signalling

Authors :
Cheng Jiang
Wang Guowei
Zhang Na
Li Fang
Shi Lina
Li Haining
Source :
Translational Neuroscience, Vol 11, Iss 1, Pp 391-401 (2020)
Publication Year :
2020
Publisher :
De Gruyter, 2020.

Abstract

Alzheimer’s disease (AD) is an ultimately fatal, degenerative brain disease in the elderly people. In the current work, we assessed the defensive capability of isovitexin (IVX) through an intracerebroventricular injection of streptozotocin (STZ)-induced AD mouse model.

Subjects

Subjects :
amyloid beta-peptide
autophagy
isovitexin
microrna-107
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571

Details

Language :
English
ISSN :
20816936
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Translational Neuroscience
Publication Type :
Academic Journal
Accession number :
edsdoj.3bcc49fb4d4f4e5ea03b9ad89067b29e
Document Type :
article
Full Text :
https://doi.org/10.1515/tnsci-2020-0109
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