Back to Search Start Over

Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering

Authors :
Zhong-Kai Cui
Soyon Kim
Jessalyn J. Baljon
Benjamin M. Wu
Tara Aghaloo
Min Lee
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Injectable hydrogels could be used to repair bone defects. Here the authors incorporate nanoclay particles into chitosan creating an interconnected microporous hydrogel and show that this hydrogel can support MSC proliferation and differentiation in vitro, and support the recruitment of native cells and bone regeneration in a mouse calvarial defect model.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3bc7df5ac80b4ff0aec78ef14a5c5d9f
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-11511-3