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Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM
- Source :
- Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
- Publication Year :
- 2023
- Publisher :
- Nature Portfolio, 2023.
-
Abstract
- Gap junction intercellular channels (GJIChs) facilitate direct communication between adjacent cells. Here, authors provide high-resolution information on dynamic structural changes in Cx43 GJICh that are necessary to understand the gating mechanism.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 14
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3ade39c189824e13bf2b039251b987e1
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-023-36593-y