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An integrated host-microbiome response to atrazine exposure mediates toxicity in Drosophila

Authors :
James B. Brown
Sasha A. Langley
Antoine M. Snijders
Kenneth H. Wan
Siti Nur Sarah Morris
Benjamin W. Booth
William W. Fisher
Ann S. Hammonds
Soo Park
Richard Weiszmann
Charles Yu
Jennifer A. Kirwan
Ralf J. M. Weber
Mark R. Viant
Jian-Hua Mao
Susan E. Celniker
Source :
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Brown et al. apply integrated omics and phenotypic screening to assess the role of the gut microbiome in modulating host resilience in Drosophila melanogaster. They find that Acetobacter tropicalis in gnotobiotic animals, is sufficient to rescue increased atrazine toxicity, which could pave the way for biotic strategies to improve host resilience to environmental chemical exposure.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.3ab3d12ed36490693a2a628de744736
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-021-02847-y