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Acute Myocardial Injury Assessed by High-Sensitivity Cardiac Troponin I Levels in Adult Patients with Early Sepsis at a Tertiary Referral Center in Mexico: An Exploratory Study

Authors :
Mauricio Alfredo Ambriz-Alarcón
Daniel Iván Arroyo-Espinosa
Héctor Meugniot-García
Juan Pablo Sánchez-Navarro
Brian Rafael Rubio-Mora
Sol Ramírez-Ochoa
Gabino Cervantes-Guevara
Miguel Robledo-Valdez
Alejandro González-Ojeda
Clotilde Fuentes-Orozco
Francisco Javier Hernández-Mora
Enrique Cervantes-Pérez
Source :
Journal of Cardiovascular Development and Disease, Vol 11, Iss 1, p 28 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

The objective of the study was to describe the frequency of acute myocardial injury (AMI) assessed by high-sensitivity cardiac troponin I (hs-cTnI) levels and to determine the possible initial risk factors (related to the characteristics of the patient, the disease, and the initial management) in a population of adult patients with early sepsis (within the first 72 h of diagnosis) in a single tertiary hospital center in western Mexico. For the inferential statistics, the proportions of the categorical dichotomous variables were compared using the chi-square test. In all analyses, p values less than 0.05 with a 95% confidence interval were considered significant. We included a total of 64 patients diagnosed with early sepsis, of whom 46 presented elevated hs-cTnI and were classified as having AMI. In our study, the frequency of AMI in patients with early sepsis was 71.87%, and no significant differences were found in all of the characteristics of patients with early sepsis with and without AMI, nor was any significant association found with any of the variables analyzed. In the population of western Mexico, the frequency of AMI in patients with early sepsis, assessed by hs-cTnI levels, is high and similar to that reported in other populations worldwide.

Details

Language :
English
ISSN :
23083425
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Journal of Cardiovascular Development and Disease
Publication Type :
Academic Journal
Accession number :
edsdoj.3a9c4d42fbbc4408a3855fab4fadfe5f
Document Type :
article
Full Text :
https://doi.org/10.3390/jcdd11010028