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Response of Escherichia coli to Acid Stress: Mechanisms and Applications—A Narrative Review

Authors :
Zepeng Li
Zhaosong Huang
Pengfei Gu
Source :
Microorganisms, Vol 12, Iss 9, p 1774 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Change in pH in growth conditions is the primary stress for most neutralophilic bacteria, including model microorganism Escherichia coli. However, different survival capacities under acid stress in different bacteria are ubiquitous. Research on different acid-tolerance mechanisms in microorganisms is important for the field of combating harmful gut bacteria and promoting fermentation performance of industrial strains. Therefore, this study aimed to carry out a narrative review of acid-stress response mechanism of E. coli discovered so far, including six AR systems, cell membrane protection, and macromolecular repair. In addition, the application of acid-tolerant E. coli in industry was illustrated, such as production of industrial organic acid and developing bioprocessing for industrial wastes. Identifying these aspects will open the opportunity for discussing development aspects for subsequent research of acid-tolerant mechanisms and application in E. coli.

Details

Language :
English
ISSN :
12091774 and 20762607
Volume :
12
Issue :
9
Database :
Directory of Open Access Journals
Journal :
Microorganisms
Publication Type :
Academic Journal
Accession number :
edsdoj.3a748d38287d4334bb554c9faab0ca96
Document Type :
article
Full Text :
https://doi.org/10.3390/microorganisms12091774