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Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Authors :
Rayabarapu Pranav Chand
Arramraju Sreenivas Kumar
Kapadia Anuj
Satti Vishnupriya
Battini Mohan Reddy
Source :
PLoS ONE, Vol 11, Iss 6, p e0153720 (2016)
Publication Year :
2016
Publisher :
Public Library of Science (PLoS), 2016.

Abstract

In our attempt to comprehensively understand the nature of association of variants at 11q23.3 apolipoprotein gene cluster region, we genotyped a prioritized set of 96 informative SNPs using Fluidigm customized SNP genotyping platform in a sample of 508 coronary artery disease (CAD) cases and 516 controls. We found 12 SNPs as significantly associated with CAD at P

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
19326203
Volume :
11
Issue :
6
Database :
Directory of Open Access Journals
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
edsdoj.3a46b83b908040f9a79f16782ffc1c0c
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pone.0153720