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The telomere length landscape of prostate cancer

Authors :
Julie Livingstone
Yu-Jia Shiah
Takafumi N. Yamaguchi
Lawrence E. Heisler
Vincent Huang
Robert Lesurf
Tsumugi Gebo
Benjamin Carlin
Stefan Eng
Erik Drysdale
Jeffrey Green
Theodorus van der Kwast
Robert G. Bristow
Michael Fraser
Paul C. Boutros
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Despite the known role of telomere length in cancer, its association with genomic features remains unclear. Here, the authors integrate telomere length, genomics, transcriptomics and proteomics in localized prostate cancer and reveal links between telomere maintenance, disease drivers and clinical outcomes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3a1b96dd7f314201be56b49c89bc022a
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27223-6