Back to Search Start Over

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Authors :
Kyung-Tae Lee
Yee-Seul So
Dong-Hoon Yang
Kwang-Woo Jung
Jaeyoung Choi
Dong-Gi Lee
Hyojeong Kwon
Juyeong Jang
Li Li Wang
Soohyun Cha
Gena Lee Meyers
Eunji Jeong
Jae-Hyung Jin
Yeonseon Lee
Joohyeon Hong
Soohyun Bang
Je-Hyun Ji
Goun Park
Hyo-Jeong Byun
Sung Woo Park
Young-Min Park
Gloria Adedoyin
Taeyup Kim
Anna F. Averette
Jong-Soon Choi
Joseph Heitman
Eunji Cheong
Yong-Hwan Lee
Yong-Sun Bahn
Source :
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Publication Year :
2016
Publisher :
Nature Portfolio, 2016.

Abstract

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3a1ac90e57ee4c81b3111fca0a130680
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms12766